Scrub Typhus: Symptoms, Treatment and Prevention

Scrub Typhus
KLE Doctor

Medically Reviewed by Dr. Priyanka Patil, General Medicine

Written by KIE Editorial Contributors

3.5 min read | Last Updated: 09 August 2025 | Published On: 09 August 2023

Sudden fever and unusual rash are signs of scrub typhus. This bacterial infection, transmitted by tiny insects called chiggers, can become dangerous if left untreated. Knowing the early symptoms, the importance of proper diagnosis and the available therapy can help prevent complications and save lives. This guide explains how scrub typhus spreads, how to detect it, and what you can do to avoid it and stay safe.

What is Scrub Typhus?

Scrub typhus is an acute febrile illness caused by the bacterium Orientia tsutsugamushi. It is transmitted through the bite of infected larval mites known as chiggers. This infection is widespread in rural and forested regions of Asia and the Pacific.

One of the causes of scrub typhus is exposure to mite-infested vegetation, which makes outdoor workers and travellers more vulnerable. If left untreated, scrub typhus can become severe, leading to organ complications.

Scrub Typhus Symptoms

Typical scrub typhus symptoms appear 6–21 days after a chigger bite and can range from mild to severe. Common signs include:

  • Sudden high fever and chills
  • Severe headache and muscle aches
  • Appearance of a red rash on the trunk and limbs
  • Formation of a dark scab (eschar) at the scrub typhus bite mark
  • Swollen lymph nodes and fatigue
  • The most common symptom is scrub typhus fever, which is often sudden and accompanied by chills.

In some cases, patients may also experience confusion, cough, or abdominal pain. Recognising these early signs is Crucial for timely scrub typhus diagnosis.

Scrub Typhus Causes and Risk Factors

Scrub Typhus disease is caused by the bacteria Orientia tsutsugamushi, which is transmitted to humans via the bite of infected chigger larvae.

Key risk factors include:

  • Spending time in rural, grassy or forested areas
  • Exposure to environments where scrub typhus insects thrive in the region
  • Lack of protective clothing during outdoor work
  • Living in endemic areas during the monsoon season

Since not all bites are noticed, paying attention to early symptoms is essential for early intervention.

Scrub Typhus Diagnosis

Accurate scrub typhus diagnosis is crucial for effective treatment. Doctors rely on:

  • Patient history and recent outdoor exposure
  • Physical examination for rash, and scrub typhus bite marks or eschar
  • Blood investigations, including the Weil-Felix test or ELISA
  • Confirmatory scrub typhus test, like PCR for bacterial DNA
  • Accurate scrub typhus diagnosis relies on a combination of clinical symptoms, exposure history, and lab confirmation

Early testing is especially crucial in preventing severe outcomes, including complications that affect the heart, lungs, or brain.

How Scrub Typhus Spreads

The infection is mainly transmitted by scrub typhus, which is carried by larval mites (chiggers) that pick up the bacteria from small mammals, such as rodents.

  • Humans are accidental hosts when bitten in an infested area
  • Scrub typhus does not spread from person to person.
  • The scrub typhus rash typically begins on the trunk and spreads to the limbs.

Scrub Typhus Treatment Options

Scrub typhus treatment is essential to avoid complications. The primary approach includes:

  • Antibiotics such as doxycycline or azithromycin
  • Supportive care with fluids and fever management
  • Early scrub typhus treatment with antibiotics can prevent life-threatening complications.
  • Monitoring for organ failure in severe cases of Disease
  • complications like pneumonia, encephalitis, or kidney failure may occur.
  • Chiggers transmit scrub typhus, the larval form of mites that carry the bacteria Orientia tsutsugamushi.

Most patients recover fully if treated within the first week of symptom onset.

Preventing Scrub Typhus

Currently, there is no licensed vaccine for scrub typhus, so prevention relies on reducing exposure to chiggers. Key steps include:

  • Wear long clothing and insect repellent in endemic regions
  • Avoid grassy or bushy areas where scrub typhus insects live
  • Clearing vegetation and maintaining hygiene around living spaces
  • Conducting routine scrub typhus tests in high-risk regions for early detection

By following these measures, the risk of infection can be significantly reduced.

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Frequently Asked Questions

Reinfection is rare but possible if you are bitten by infected chiggers again in endemic areas because natural immunity is not always lifelong.

Symptoms usually develop 6–21 days after the bite of an infected chigger, with fever often being the first noticeable sign.

No, scrub typhus is not contagious between humans. It is only transmitted by scrub typhus, which is caused by infected chigger bites.

The presence of a dark scab, known as an eschar, at the site of a scrub typhus bite mark is a key diagnostic clue, although not all patients develop one.

Currently, there is no commercially available vaccine. Prevention relies on protective clothing, insect repellents, and avoiding high‑risk areas.

Yes, scrub typhus is a serious and potentially life-threatening condition if left untreated. It can lead to severe complications such as brain inflammation, pneumonia, or kidney failure.

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