Marasmus: Causes, Symptoms, Diagnosis, and Treatment

Marasmus
KLE Doctor

Medically Reviewed by Dr. Smruthi, Paediatrics

Written by KIE Editorial Contributors

3.5 min read | Last Updated: 13 August 2025 | Published On: 13 August 2023

Marasmus is a severe form of protein-energy malnutrition that primarily affects infants and young children. It occurs when the body is deprived of both calories and protein for a prolonged period. Characterized by extreme thinness, muscle wasting, and stunted growth, marasmus can be life-threatening if not diagnosed and treated early.

This condition is most common in regions with food scarcity, poor sanitation, and inadequate healthcare access. However, marasmus can also result from chronic illnesses or neglect in any part of the world.

Marasmus Causes

Understanding the marasmus causes is critical for prevention and early intervention. The most common causes include:

  • Prolonged calorie and protein deficiency
  • Chronic infections like tuberculosis or HIV/AIDS
  • Gastrointestinal disorders affecting nutrient absorption
  • Poor breastfeeding practices
  • Early weaning without adequate nutrition
  • Poverty, food insecurity, and famine
  • Neglect or inadequate parental care

In many cases, marasmus develops gradually over time due to continuous undernourishment and recurring infections.

Marasmus Symptoms

The marasmus symptoms can be both physical and behavioral. Early identification of the signs and symptoms of marasmus can help in timely medical intervention.

Common symptoms include:

  • Severe weight loss and emaciated appearance
  • Muscle wasting and lack of subcutaneous fat
  • Sunken eyes and hollow cheeks
  • Dry, thin, and wrinkled skin
  • Stunted growth in children
  • Weak immune system leading to frequent infections
  • Irritability, lethargy, and reduced activity
  • Delayed developmental milestones in infants

Diagnosis of Marasmus

The diagnosis of marasmus is typically clinical, supported by anthropometric measurements and lab tests. Key diagnostic tools include:

  • Weight-for-age and weight-for-height comparisons
  • Body Mass Index (BMI) in older children or adults
  • Mid-upper arm circumference (MUAC) for rapid screening
  • Blood tests to detect anemia, electrolyte imbalances, or infections
  • Nutritional history and physical examination

Early diagnosis is essential to reduce complications such as organ failure, dehydration, and hypoglycemia.

Marasmus Treatment

Marasmus treatment focuses on gradual nutritional rehabilitation, treating underlying infections, and restoring the body’s fluid and electrolyte balance. A structured and compassionate care plan includes:

1. Medical Stabilization:

  • Managing dehydration and electrolyte imbalance
  • Treating infections with appropriate antibiotics
  • Monitoring and treating hypoglycemia and hypothermia

2. Nutritional Rehabilitation:

  • Initiating refeeding with energy-dense, easily digestible foods
  • Introducing therapeutic foods like F-75 and F-100 formulas
  • Gradual reintroduction of proteins and fats
  • Supplementing with vitamins and minerals

3. Ongoing Care and Follow-Up:

  • Nutritional counseling for caregivers
  • Immunizations and hygiene education
  • Monitoring growth and recovery progress

In severe cases, hospitalization and a multidisciplinary team approach may be required.

Marasmus vs Kwashiorkor

It’s important to differentiate marasmus from kwashiorkor, another form of malnutrition. While marasmus involves severe wasting and calorie deficiency, kwashiorkor is caused by a lack of protein and often presents with edema (swelling).

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Frequently Asked Questions

Yes, with timely medical care, proper nutrition, and follow-up, marasmus can be treated and reversed in most cases.

Marasmus is a severe form of malnutrition with visible muscle wasting, while being underweight might not always indicate nutrient deficiency or disease.

While more common in children, adults with chronic diseases, poor dietary intake, or substance abuse may also develop marasmus.

Energy-rich and protein-dense foods like milk, eggs, pulses, cereals, and therapeutic feeding formulas aid in recovery.

Mild cases may be managed at home with guidance, but moderate to severe marasmus often requires hospital care for monitoring and nutritional support.

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